Johnson & Johnson is recruiting for a Postdoctoral Fellow- Cell Therapy in the Johnson & Johnson Innovative Medicine (J&J IM) group located in West Chester, PA

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.

For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges.

We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.

At Johnson & Johnson, we all belong.

Johnson & Johnson Innovative Medicine (J&J IM) develops treatments that improve the health of people worldwide. Research and development areas encompass oncology, cardiovascular and metabolic disorders, immunology, pulmonary hypertension, neuroscience, and infectious disease. Our goal is to help people live longer, healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market - from patients to practitioners and from clinics to hospitals. To learn more about J&J Innovative Medicine, visit https:// https://www.jnj.com/innovative-medicine.

The J&J IM Discovery, Product Development, & Supply (DPDS) Postdoctoral Fellowship Program helps early career scientists gain the training and experience needed to further their careers while addressing the needs of global healthcare. Postdocs work side-by-side with DPDS scientists on innovative research projects and have the opportunity to present and publish their work. They also learn the functional role of scientists in the pharmaceutical industry and receive valuable career advice from mentors while building a network of professional contacts and developing the skills needed to advance their careers.

The Cell Therapy group of Janssen Therapeutics Discovery seeks an enthusiastic postdoctoral fellow to join the Cell Therapy Gene Editing team, which investigates and implements genetic engineering strategies to enhance the activity of CAR T cells. Your project will use combinatorial pooled screening approaches to discover mechanisms controlling T cell fitness. Success in this project will be enabled by strong molecular and cell biology skills, along with the ability to collaborate well with internal experts in T cell biology, functional genomics, and bioinformatics. Start the next phase of your career with us and contribute towards developing best-in-class cell therapies!

The anticipated start date for this role is October 14th, 2024.

Key Responsibilities:

• Isolating, culturing, and engineering, primary human T cells
• Evaluating T cell fitness through flow cytometry, scRNA-seq, and other methods
• Using a variety of molecular engineering approaches (viral transduction, CRISPR, etc) to screen for functional biology
• Collaborating with internal colleagues to successfully meet project goals

Qualifications

Education:

• PhD in Molecular Biology, Cell Biology, Immunology, Genetics or a related discipline
• Degree must be completed in the last 3 years, or by October 2024 for current students

Required:

• Demonstrated track record of success in independent scientific research, including peer-reviewed publications in scientific journals
• Molecular and cell biology skills, including mammalian cell culture, DNA/RNA extraction, PCR, and flow cytometry
• Experience with genetic engineering techniques, including viral transduction and CRISPR/Cas
• Outstanding capacity to learn quickly and rigorously draw accurate conclusions from data
• Self-motivated, with the ability to both independently advance research programs and to collaborate well in a multi-disciplinary environment
• Excellent interpersonal, verbal, and written communication skills in English
• Ability to stay organized, plan for complicated long-term experiments, and maintain detailed records

Preferred:

• Foundational knowledge of T cell biology, including hands-on experience with primary human T cells
• Familiarity with high-throughput pooled screening techniques
• Ability to draw conclusions from analyzed single cell RNA sequencing data

The salary for this position is $95,000/year, this position is eligible for a sign-on bonus. This is a two year duration based role that has eligibility for severance.

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis.

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs:

• Medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
• Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).
• This position is eligible to participate in the Company's long-term incentive program.
• Employees are eligible for the following time off benefits:
• Vacation - up to 120 hours per calendar year
• Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
• Holiday pay, including Floating Holidays - up to 13 days per calendar year
• Work, Personal and Family Time - up to 40 hours per calendar year

For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits

This job posting is anticipated to close on July 24th, 2024 . The Company may however extend this time-period, in which case the posting will remain available on https://www.careers.jnj.com to accept additional applications.

Johnson & Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law.

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