Principal Scientist, Bio-Assay Automation

Billerica, Massachusetts


Employer: Merck Group
Industry: 
Salary: Competitive
Job type: Full-Time

By unlocking the power of data AI for drug discovery (AIDD) has the potential to enable personalized medicine and change patient lives. An M-Ventures funded biotech start-up is poised to seize the opportunity at the intersection between the Healthcare and Life Science Divisions of Merck, KGaA Darmstadt, Germany. Our mandate is to think big and reach across teams to leverage the full capabilities of the organization. For more than 350 years and across the world we have passionately pursued our curiosity to find novel and vibrant ways of enhancing the lives of others. As the Senior Scientist, Bio-Assay Automation, you will be part of the Drug Discovery Automation group responsible for designing, managing, and leading the automated Bioassay systems, part of our cutting-edge cloud lab infrastructure providing drug discovery and chemistry services to Pharmaceutical and Biotech customers. The ideal candidate will have a strong background in cell biology and experience developing and implementing automated bioassay systems and processes in pharmaceutical R&D settings. You will be responsible to:Lead the design, development, and implementation of new automated, high throughput bioassay systems for small molecule testing.Transfer bioassay procedures in to automated biotesting protocols, troubleshoot and optimize new assays in line with project chemistry requirements.Plan and execute experiments to optimize the efficiency and reproducibility of Biotesting systems with high accuracy and efficiency.Collaborate with cross-functional teams, including process engineers and software developers, procurement, sourcing, facilities, and project management. Develop and implement quality control procedures to ensure that Bio-assay tests are carried out accurately and consistently.Lead automation project planning, timeline, milestones, success criteria and resources management including engineers, equipment, lab space etc. for new lab build-outs.Develop and manage the laboratory's budget, ensuring that all expenditures are justified and aligned with the laboratory's goals and objectives.Prepare and present technical reports, research findings, and presentations to internal and external stakeholders. Location: Billerica, MATravel: <10% Who You Are:Minimum Qualifications:At least 8 years of relevant experience in small molecule bio-assay testing in the pharmaceutical/biotech industryHand-on experience in automated biotesting workflows, including ADME assay development.Knowledge of analytical instrumentations such as HPLC/MS/MS, Acoustic liquid handlers, MTP spectral readers, working with dynamic scheduling orchestrating software. Excellent communication and interpersonal skills, with the ability to work effectively with customers, suppliers, and other stakeholders.Participate and thrive in an interactive, dynamic, team oriented culture Preferred Qualifications:PhD degree in Cellular Biology, Cellular Bio-Chemistry, Biotechnology or related fieldsStrong experience in implementing automated Bio-Assay processes, including the use of robotic systems.Detailed knowledge of scheduling software design and integration across an automated laboratory environment.Experience with automation project development from concept, preliminary and final design, through construction, installation and project closure strongly preferred with cost analysis.Comfortable working in an entrepreneurial environment, agile and face-paced teamsSelf-driven, results-oriented leader with proven collaborative working style

Created: 2024-07-01
Reference: 275342
Country: United States
State: Massachusetts
City: Billerica