Expected Starting Salary Range: 23.02 - 28.06 (RAIII) 26.42 - 32.71 (RAIV) 31.43 - 39.59 (Sr. RA)

The Spearman Lab research focuses on the study of HIV biology, including the assembly process of the virus. They study how the virus interacts with host cells, especially with the host trafficking machinery. We are investigating how the HIV envelope protein becomes incorporated into budding particles and defining the cellular pathways that direct this process. Another project focuses on the cellular pathways that direct the internalization of HIV particles by macrophages and microglia, and how these cell types transmit virus to other cells in their environment. We also direct vaccine trials for adults and children, which extends my research interests beyond HIV to Ebola, SARS-CoV-2 and other pathogens.

REPRESENTATIVE RESPONSIBILITIES

• Supervise & assist lab personnel in technical procedures

Propose and design projects for rotating graduate and undergraduate laboratory students. Train postdoctoral fellows, graduate students and laboratory personnel and others on procedures performed in the laboratory and in laboratory techniques. Maintain an integral role in the laboratory's meetings, presentations, and publications. Present information on research and laboratory work to others at laboratory meetings, journal clubs, and seminars. Set up and maintain laboratory website.

• Leadership

May act as a mentor to more junior staff, serve as the contact for resolution of complex issues, provide education, guidance and work direction. May provide input and feedback to managers on hiring decisions, professional development and performance management.

• Design & Perform experiments and record data

Follow research protocols. Independently reproduce, evaluate, research and improve techniques currently used. Answer scientific questions posed by supervisory faculty. Maintain accurate and detailed records of all laboratory work and experiments. Analyze data, perform statistical and graphical analysis of data, and interpret results. Author material for reports, publications, journal articles, and abstract

• Develop, set up and verify new procedures

Innovate and adapt new methods to existing procedures and modify current experiments through scientific knowledge and intuition. Standardize and establish new published procedures. Evaluate innovative techniques. Develop new assays and new protocols; design formats. Discuss relevant insights about experimental results with primary investigator and provide useful recommendations and analysis. Develops new & critical technology for the laboratory's progress.

• Lab Administration

Troubleshoot and correct erroneous results or problems with laboratory equipment. Maintain and repair equipment; monitor proper use by personnel. Maintain optimal protocol and assay accuracy by conducting regular quality and reproducibility checks. Maintain inventory of laboratory supplies and equipment; order supplies from vendors and storeroom. Maintain stocks of chemicals and solutions. Purchase and ensure proper handling and care of laboratory animals. Assist in preparing, writing, and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests. Prepare, approve, and initiate check requests; track funding, maintain accurate balance, and resolve any discrepancies. Provides appropriate compliance checks as assigned and may be responsible for all internal laboratory record keeping with respect to compliance.

Qualifications:

EDUCATION/EXPERIENCE

Required for RAIII:

• Bachelor's degree in a related field AND 1 year of directly related experience OR Master's degree in a related field

Required for RAIV:

• Bachelor's degree in a related field

• 3 years of experience in related job discipline OR Master's degree and 2 years experience

Required for SRA:

• Bachelor's degree in a related field

• 7 years of experience in related job discipline OR Master's degree and 6 years experience

Cincinnati Children's is proud to be an Equal Opportunity Employer that values and treasures Diversity, Equity, and Inclusion. We are committed to creating an environment of dignity and respect for all our employees, patients, and families (EEO/AA).