The Leclerc Laboratory at the University of Virginia, Department of Anesthesiology, seeks applications for a Research Technician or Lab Specialist .

The Leclerc Lab focuses on elucidating the mechanisms for the clearance of neurotoxic metabolites from the brain following hemorrhagic stroke. Normally, blood is not present within the brain aside from that which is contained within the vasculature. When bleeding occurs , red blood cells become unstable and release a myriad of neurotoxic molecules. The glymphatic pathway is a special clearance pathway within the brain that facilitates bulk flow washout of molecules to the periphery . This research focuses on how various anesthetic agents interact with the glymphatic pathway to facilitate the clearance of neurotoxic metabolites after hemorrhagic stroke .

The experiments proposed utilize cutting-edge in vivo and in vitro techniques and represent a unique research niche that bridges the fields of Anesthesiology and Neuroscience . This position will require the ability to perform both routine lab functions as well as more advanced neuroscience procedures and protocols . Routine lab functions may include managing the mouse colony, genotyping, making solutions, ordering lab supplies , maintaining inventor ies , and organizing and maintaining records and lab SOPs. Advanced neuroscience procedures may include performing stereotaxic surgery on mice , two photon microscopy , administering pharmaceutical agents to mice, neuro-behavioral monitoring of mice, and performing histology , western blotting, and other forms of microscopy. In addition to the above job responsibilities, other duties may be assigned.

This position will report to the Principal Investigator (PI). All team members meet individually with the PI at least weekly to summarize their progress and troubleshoot their projects. They will also work closely with other team members within the Department of Neuroscience.

Applicants will be considered for a Lab and Research Technician 1 or 2 or a Lab Specialist position, based on the degree of their prior education and laboratory experience.

Minimum Qualifications:

• High school diploma or equivalent
  
• At least 1 year of laboratory research and/or surgical experience working with mice or other small animals, to include experience gained as a student ( bachelor's degree will be considered in lieu of experience)
  
• Proficient with Microsoft Word , Excel , and PowerPoint
  
• C omfortable learning various computer software systems and manipulating, computing, and analyzing data to include mathematical calculations , sta ti stical analyses and data presentation
  
• Excellent organizational and timeline management skills
  
• Able to perform library and literature searches
  
• Work effectively with medical and undergraduate students to guide projects and meet deadlines
  
• Demonstrate expertise in troubleshooting problems and recommending solutions
  
• Have strong ability to work independently and function well as part of a team
  
• Comfortable handling rodents
  

Preferred Qualifications:

• Bachelor's or higher degree, particularly if in neuroscience and/or pharmacology or related field of study
  
• Over 3 years of laboratory experience , with particular emphasis on significant experience working with rodents
  
• Interest in basic neuroscience, stroke, and/or anesthesiology research
  
• Experience with two-photon microscopy and cranial windows in mice
  
• Experience with stereotactic surgery in mice
  
• Experience with neurobehavioral monitoring in mice
  

UVA Anesthesiology provides an environment where expertise and passions thrive, utilizing our extraordinary team of anesthesia physicians, trainees, nurses and staff to advance patient care within UVA Health. With excellence in physician leadership, research, education and innovations, we strive to improve perioperative outcomes, establish unparalleled practices in patient care, and advance the field of anesthesiology globally. Clinical and Basic Science Research are an essential part of the mission in the UVA Department of Anesthesiology.

PHYSICAL DEMANDS

This position can spend extensive periods of time standing and squatting while conducting experiments or caring for animals. Also requires keyboarding and other bench work and animal procedures requiring finer finger manipulation .

For additional information about the position, please contact Jenna Leclerc , MD, PhD at cxx 3cm @virginia.edu

This position is located in Charlottesville, VA.

This position is a restricted position and is dependent upon project need, availability of funding and performance. This is a Non-Exempt level, benefited position . For more information on the benefits at UVA, visit hr.virginia.edu/benefits .

This position will remain open until filled . The University will perform background checks on all new hires prior to employment . A completed pre-employment health screen is required for this position prior to employment .

To Apply:

Please apply through Workday , and search for R0054027 . Internal applicants must apply through their UVA Workday profile by searching 'Find Jobs' . Complete an application online with the following documents:

• CV
  
• Cover letter
  

Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission . Applications that do not contain all required documents will not receive full consideration.

References will be completed via UVA's standardized process Skill Survey. A total of five references will be requested via Skill Survey during the final phase of the interview process.

For questions about the application process, please contact Ashley Cochran, Senior Recruiter at alc6dk@virginia.edu .

For more information about UVA and the Charlottesville community please see http://www.virginia.edu/life/charlottesville and https://embarkcva.com/ .

The University of Virginia, i ncluding the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician's Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.