Piper Life Sciences is seeking a Scientist to support the Antibody Discovery team of a growing biotech company in Rockville, MD. This role supports groundbreaking neurological research for various life-threatening diseases.

Responsibilities for the Senior Scientist include:
• Utilize phage/yeast display or hybridoma technologies to discover antibody hit molecules used in neurology research.
• Engineer and optimize antibody lead molecules through sub-library, humanization, and affinity tuning techniques.
• Characterize antibodies using various in vitro biochemical and cellular assays.
• Utilize mammalian expression systems to express and purify biologics and generate the desired antibody expressions.
• Analyze, interpret, and report data results from the study. Identify areas for improvement and troubleshooting as needed.
• Collaborate with internal and external teams including CROs, translational medicine, and CMC.
• Supervise and mentor Research Associates and Scientists as needed.

Qualifications for the Senior Scientist include:
• 3+ years of experience with antibody discovery (particularly bacteria/yeast phage display), mammalian cell culture, and biochemical assays in an academic or industry setting.
• Master of Science in Biochemistry, Cellular Biology, Molecular Biology, Pharmacology, Immunology, Neurology, or related field is highly desired. PhD is preferred.
• Experience with FACS, ELISA, Octet, etc. is highly preferred.

Compensation for the Senior Scientist includes:
• Salary Range: approximately $90,000 - $110,000 annually, commensurate with experience
• Full Benefits: Medical, Dental, Vision, 401k, Bonus, Stock Options, PTO

Protein biochemistry, protein-protein binding, antibody discovery, antibody research, antigen, biochemistry, biochemical assay, quantitative analysis, protein interactions, gene expression, gene cloning, genetic cloning, cell culture, mammalian cells, FACS, binding assay, cell surface binding, functional assay, neurobiology, neurology, cns, central nervous system, spr binding assay, octet, kd, kinetics, phage, yeast display, therapeutic, preclinical research, r&d, research and development. Small molecule, biologics, in vitro, hybridoma, protein expression, protein purification

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