Senior Scientist, Division of Infectious Diseases

The Marie Lab in the Department of Medicine at the University of Virginia seeks a Senior Scientist. The research in the Marie Lab seeks to understand the mechanisms through which parasites invade host cells, and how the host immune system coordinates defense, inflammation and tissue homeostasis. In this context, we take a special interest in understanding host cell gene expression during infection in both in vitro and in vivo systems. The Senior Scientist is expected to have sufficient experience and background to organize small research groups and perform assigned tasks on their own initiative with minimal direction.

Responsibilities include:

• Organize small research groups

• Supervise Lab Technicians and other lab workers

• Direct mouse infection experiments

• Direct clinical data analysis by students

• Interface with biostatisticians to determine appropriate data analysis methods

• Manage ACUC protocols and approvals and ensure compliance with approved protocols and regulations

• Mange biosafety inventory and ensure compliance with biosafety regulations

• Manage IRB regulations governing human subjects research and maintain current CITI certification for human subjects clinical research

• Ensure all human subjects work is conducted in compliance with IRB regulations and that all students are properly trained

• Maintain detailed records of data and data analysis

• Oversee deposition of data in public databases

• Supervise ordering by Lab Technician

• Prepare figures for presentations and for publication

• Write grants and manuscripts

• Perform assigned tasks on their own initiative with minimal direction

• In addition to the above job responsibilities, other duties may be assigned

The position is a 12-month appointment with the possibility of renewal contingent upon satisfactory performance and the availability of funding.

Minimum Qualifications:
Education: Doctoral degree in Bioengineering, Microbiology, or other physical or biological science

Preferred Qualifications/Experience:

• Ability to communicate expectations and progress clearly, asking for help when needed
• Ability to work independently and as part of a team and ability to respond to feedback.
• Highly organized, detail-oriented, and reliable.
• Quantitative analysis of immunological responses by high dimensional flow cytometry and ELISA
• Advanced microscopy techniques including TEM
• Quantitative PCR (DNA, RNA, and genotyping)
• Murine models of enteric infection
• Histologic sample preparation, processing, and analyses
• Advanced data and biostatistical analyses including linear mixed effects models using R
• RNA-sequencing experimental design and analyses
• Microbial profiling using advanced sequencing

PHYSICAL DEMANDS

This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs and may occasionally require time outside of normal work hours.

The position will remain open until filled. This is an exempt-level, benefitted position. The University will perform background checks on all new hires prior to employment. A pre-employment health screening is required. This position is located in Charlottesville, VA.

To Apply:

Please apply through the UVA job board , and search for R0063967. Internal applicants must apply through their UVA Workday profile by searching 'Find Jobs'. Complete an application online with the following documents:

• CV/Resume
• Cover letter
• Contact information for 3 references

Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission. Applications that do not contain all required documents will not receive full consideration.

For questions about the application process, please contact Jessica Russo, Academic Recruiter, at sxv9zv@virginia.edu .

For more information on the benefits available to postdoctoral associates at UVA, visit postdoc.virginia.edu and hr.virginia.edu/benefits .

The University of Virginia, i ncluding the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician's Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex, pregnancy, sexual orientation, veteran or military status, and family medical or genetic information.