BRCF Transgenic Core Laboratory Specialist

How to Apply

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Job Summary

The Biomedical Research Core Facilities (BRCF), as part of the Medical School's Office of Research (OoR), has an opening in the Transgenic Animal Model Core. The BRCF Transgenic Core was established in 1989 to provide access to transgenic animal technology in an efficient & effective manner. Researchers consult with the Core in all phases of genome editing, transgenic and gene targeting research from experimental design to mouse breeding. The Transgenic Core also offers a full suite of cryopreservation and assisted reproduction (IVF) services. The Core's mission is to provide access to complex technology that allows Principal Investigators to focus on their research instead of developing the tools for their research.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world?s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

• Excellent medical, dental and vision coverage effective on your very first day
• 2:1 Match on retirement savings

Responsibilities*

Provide support with assisted reproductive technology program including:
In vitro fertilization of mouse eggs with mouse sperm.
Cryopreservation of mouse sperm and embryos.
Surgical transfer of embryos to surrogate female mice.
Occasional weekend and weekly night work for superovulation treatment.

Assist with molecular biology program.
Perform methods including DNA purification, PCR reactions, and NGS library prep for genotype and CRISPR gRNA activity.

Animal Colony and Room Management
Manage the mouse and rat transgenic production colonies
Tissue collection and tagging for identification of mice and rats
Tissue sample preparation for DNA extraction
Weaning and distribution of mice and rats to on-campus and off-campus clients
Superovulation for production of embryos for genetic manipulation.
Postoperative care
Inspection preparation and compliance to OSEH, AAALAC and IACUC
Prepare and manage Animal Use Protocols, animal purchases, animal transfers and exports

Provide customer service including communicating with clients about projects and animal breeding plans to maintain their animal colony strains used in their research; general laboratory maintenance

Required Qualifications*

• Bachelor's degree and 6+ years of paid laboratory experience
• Demonstrated experience in molecular biology procedures such as DNA purification, PCR, molecular cloning, and NGS library preparation
• Prior knowledge and experience working in a research animal management electronic system
• Significant paid experience with animal handling, sampling, husbandry, and breeding
• Demonstrated experience of highly organized record keeping
• Highly developed communication skills with people of diverse backgrounds
• Attention to detail, punctuality, and occasional weekend work required
• Ability to work independently with limited supervision as required
• Excellent interpersonal skills and ability to work with others in a collaborative environment
• Strong oral and written communication skills
• Proficient in Microsoft office software

Desired Qualifications*

• Previous experience either working in a transgenic core or in a laboratory that has used transgenic rodents in research.
• Demonstrated experience working with mice and rats.
• Demonstrated experience in tissue cell culture.

Modes of Work

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes .

Additional Information

The Michigan Medicine Biomedical Research Core Facilities are firmly committed to advancing Inclusion, Diversity, Equity, Accessibility, and Belonging which are core values at the Office of Research. Our community supports recruiting and cultivating a diverse workforce, as it is a reflection of our commitments to serve the diverse people of Michigan and the world. We strive to create a work culture where every team member feels respected, valued, and safe.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.

Job Detail

Job Opening ID

253947

Working Title

BRCF Transgenic Core Laboratory Specialist

Job Title

Research Lab Specialist Senior

Work Location

Ann Arbor Campus

Ann Arbor, MI

Modes of Work

Onsite

Full/Part Time

Full-Time

Regular/Temporary

Regular

FLSA Status

Exempt

Organizational Group

Medical School

Department

MM BRCF Transgenic Animal Core

Posting Begin/End Date

8/30/2024 - 9/06/2024

Career Interest

Research