Post-Doctoral Associate

Twin Cities, Minnesota


Employer: University of Minnesota
Industry: Campus Operations
Salary: Competitive
Job type: Full-Time

Provide structural biology support to ensure that translational medicinal chemistry projects in the Institute of Therapeutics Discovery and Development are advanced to milestones in an effective manner.

Job Duties/Responsibilities:
Laboratory-based Medicinal Chemistry (80%):
- Designs, plans, implements, and evaluates complex, multifaceted research projects in
structural biology while remaining current on technological and scientific developments in
the field and their potential application into experimental plans.
- Works with supervisor for experimental planning and executes scientific experiments to
sustain data generation and evaluation.
- Evaluates, suggest alternate methods, modify, or develop new procedures and techniques
to aid in the investigation of structural biology research problems or programs in the
supervisor's laboratory.
- Modifies protein expression to maintain efficiency and quality, searches for better ways to
effectively achieve end results by, for example, scheduling work steps, arranging/ rearranging the way work is generally performed, and adding or deleting elements of
processes as necessary.
- Discusses and plans new avenues of research with supervisor. Will work under the general
supervision of her supervisor but has the discretion to make daily operational decisions and
work independently.
- Documents work appropriately in electronic laboratory notebooks. Ensures that structural
biology data prepared in the laboratory conform to the quality required for publication.

Writing and Editing: (15% of time):
- Assists with the preparation of scientific manuscripts and works with journal
editors/reviewers to insure effective publication.
- Assists in the drafting reports to communicate her work to the project team and to our
funding sources.

Safety: (5% of time):
- Adheres to best practices of safety and chemical hygiene as mandated by the Department of
Neurology and the Department of Medicinal Chemistry at the University of Minnesota.

Qualifications

Required Qualifications:
- Must have PhD in medicinal chemistry with a strong emphasis in structural biology.
- Demonstrated experience working with international collaborators on crystallization of small
molecule compound complex with proteins and the solution of these structures using
computational methods.
- Knowledge of the processes for uploading data to the PBD (protein databank).
- Knowledge typically acquired by structural biology work in a rigorous academic setting.
- Detailed knowledge of the methods structural biology including plasmid design, protein
production and purification, and methods of protein-complex crystallization.
- Strong scientific writing skills.
- Superior record keeping and documentation skills.
- Excellent communication (both spoken and written) skills.
- Demonstrated ability to lead and complete complex projects.
- Demonstrated knowledge of chemical safety and chemical hygiene strategies.
- Demonstrated knowledge of typical software packages such as (but not limited to) Microsoft Office, ChemDraw, Graphpad Prism and software typically used by structural biologists in the solution of crystal structure data.
- Ability to work completely independently.
- Strong collaborative skills.

Preferred Qualifications:
- Experience in the design and expression of mutant proteins suitable for crystallization.

Benefits

Working at the University

At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work.

The University also offers a comprehensive benefits package that includes:
  • Competitive wages, paid holidays, and generous time off
  • Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program
  • Low-cost medical, dental, and pharmacy plans
  • Healthcare and dependent care flexible spending accounts
  • University HSA contributions
  • Disability and employer-paid life insurance
  • Employee wellbeing program
  • Excellent retirement plans with employer contribution
  • Public Service Loan Forgiveness (PSLF) opportunity
  • Financial counseling services
  • Employee Assistance Program with eight sessions of counseling at no cost
  • Employee Transit Pass with free or reduced rates in the Twin Cities metro area

Please visit the Office of Human Resources website for more information regarding benefits.

How To Apply

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

Diversity

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Employment Requirements

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

About the U of M

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America’s Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).

Created: 2024-06-09
Reference: 361808
Country: United States
State: Minnesota
City: Twin Cities


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