Postdoctoral Fellow - Lymphoma-Myeloma - Research

Researchers interested in postdoctoral fellowships are invited to apply for positions as part of the group led by Dr. Sheeba Thomas, Professor and Dr. Robert Orlowski, Florence Maude Thomas Cancer Research Professor and Director of the Myeloma Section in the Department of Lymphoma/Myeloma at The University of Texas MD Anderson Cancer Center. Our focus is on developing an expanded understanding of the molecular pathobiology of multiple myeloma and related disorders, validating novel targets and therapeutics that can be translated to the clinic, and understanding mechanisms of resistance that could serve as biomarkers and/or targets for chemosensitization. Current projects of interest focus on the activity of a novel, home-grown set of patented monoclonal antibodies that are showing immunomodulatory and direct cytotoxic activity against a variety of tumor models as naked antibodies, antibody-drug conjugates, and in chimeric antigen receptor guided T-cells.

LEARNING OBJECTIVES
Our research focuses on developing novel adoptive T-cell therapy approaches for hematological malignancies and solid tumors. The candidate will be involved in developing and evaluating novel adoptive T-cell therapy strategies including CAR-T and TCR-T, and viral- and tumor antigen-specific T cells in both in vitro and in vivo models. Candidates should be self-motivated, career-oriented, and should be capable of troubleshooting.

ELIGIBILITY REQUIREMENTS
Applicants should be graduates with an M.D. and/or Ph.D. in immunology/immunotherapy with experience in T-cell culture, assays to assess T-cell function, animal experiments with syngeneic or xenograft tumor models, and T-cell biology. Experience in working with human immune and tumor cells, animal studies, retrovirus and/or lentiviral generation, molecular cloning, transduction of primary T cells, gene editing, and flow/mass cytometry is preferred. Excellent verbal and written communication skills, multiple publications, and strong reference letters are required.

POSITION INFORMATION
MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000 . depending on the number of years of postgraduate experience. MD Anderson trainee compensation also includes:

Paid medical benefits (zero premium) starting on the first day for trainees who work 30 or more hours per week
Group dental, vision, life, AD&D, and disability coverage
Paid education, vacation, and sick leave
Paid institutional holidays, wellness leave, childcare leave, and other paid leave programs
Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans
Employer-paid life, AD&D, and an illness-related reduced salary pay program
Health Savings Account and Dependent Care Reimbursement flexible spending accounts
Fertility benefits
State of Texas longevity pay
Extensive wellness, fitness, employee health programs, and employee resource groups

FACULTY MENTOR
Dr. Sheeba Thomas, Dr. Robert Orlowski, and Florence Maude Thomas