Research Assistant II/III - Reproductive Biology - Chen Lab

Expected Starting Salary Range: 19.73-24.05 (RAII) 23.02 - 28.06 (RAIII)

A new life begins at fertilization of the egg by the sperm. Following fertilization, the terminally differentiated gametes are converted into a totipotent zygote. During parental-to-zygotic transition, much of the parental epigenomes are reset except for imprinted loci. This resetting process is known as epigenetic reprogramming. The Chen Lab aims to understand epigenetic reprogramming by studying 1) chromatin dynamics and functions during parental-to-zygotic transition, 2) key factors required for totipotency acquisition, and 3) biological significance of transposon expression dynamics in early development.

REPRESENTATIVE RESPONSIBILITIES

• Perform experiments and record data

Follow research protocol. Maintain accurate and detailed records of all laboratory work and experiments. Analyze data; perform statistical and graphical analysis of data. Design and execute daily laboratory experiments in coordination with senior laboratory personnel. Reproduces and evaluates techniques and results for accuracy. Apply standard protocols to specific experiments, research and improve current methods, and evaluate innovative techniques. Assists in training students and new/junior laboratory personnel in laboratory techniques and equipment operation.

• Lab Administration

Troubleshoot and correct erroneous results or problems with laboratory equipment. Reproduces and evaluates techniques and results for accuracy. Maintain inventory of laboratory supplies and equipment. Maintain cell cultures. Operate standard laboratory equipment. Use and maintains laboratory equipment appropriately. Responds to obviously erroneous results or problems with equipment. Assists in daily operations of the laboratory including answering phone, maintaining lab supplies, organization, and cleanliness.. Provides appropriate safety monitoring checks as assigned (radiation safety, biosafety, etc.).

• Serve as a Resource

Demonstrate competence in specific knowledge, skills and behaviors. Effectively communicate with team members and contribute to their growth by sharing knowledge, experience, and skills. Stay abreast of changes in key systems. Serve as a resource to the department in specific area(s).

• Customer Service

Maintain/manage strong working relationships with clients, colleagues, and other key stakeholders. Respond to requests quickly and effectively. Identify and understand customer needs and expectations and meets them. Communicate any relevant information to clients, colleagues, and other key stakeholders.

Qualifications:

EDUCATION/EXPERIENCE

Required for RAII:

• High school diploma or equivalent AND 2 years of work experience in a related job discipline OR

Preferred:

• Bachelor's degree in a related field

Required for RAIII:

• Bachelor's degree in a related field AND 1 year of directly related experience OR Master's degree in a related field

Cincinnati Children's is proud to be an Equal Opportunity Employer that values and treasures Diversity, Equity, and Inclusion. We are committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/AA/M/F/Veteran/Disability