Division: Molecular and Human Genetics

Work Arrangement: Onsite only

Location: Houston, TX

Salary Range : $28,710 - $38,830

FLSA Status: Nonexempt

Summary

Research technician II will be responsible for managing the laboratory to support our different projects on understanding the role of repetitive DNA in human diseases. This role would be ideal for someone who has experience in running a laboratory and is familiar with mammalian cell culture and molecular biology. They will use their expertise in management and experimentation in the lab to carry out procurement of lab materials, maintain cell cultures, and perform molecular cloning experiments.

The Erwin Lab investigates the functional role of repetitive DNA with a focus on translating these discoveries into new diagnostics and therapies for human health. The lab research vision is based on two discoveries. First, we developed a new class of synthetic transcriptional regulators that target repetitive DNA sequences with high affinity and specificity (Erwin et al, Science 2017). The resulting patents were licensed by a startup company who initiated a Phase 1 clinical trial for patients with Friedreich's ataxia earlier this year. Second, we uncovered that recurrent repeat expansions represent an overlooked source of genetic variation in cancer (Erwin et al, Nature, 2023). The Erwin Lab is building on these discoveries with the development and application of tools in genomics, molecular biology, and chemical biology. The goal is to uncover the functions of repetitive DNA, the final frontier of the genome.

Job Duties

• Performs all necessary management tasks for supporting research needs that requires the use of administrative and technical skills
• Orders laboratory supplies and equipment.
• Manages reagent stocks, cell lines, DNA vectors, and technical protocols
• Maintains mammalian cell cultures.
• Performs and optimizes cell culture experiments.
• Prepares and conducts molecular cloning experiments.

Minimum Qualifications

• Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
• No experience required.

Preferred Qualifications

• Experience in molecular cloning and mammalian cell culture.
• Experience in management tasks in a research laboratory.
• Experience in molecular biology.
• Experience with human cancer cell lines is a plus.
• Be able to ensure the smooth implementation of all our research projects by meticulously managing our stocks and equipment.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

19193

Requisition ID: 19193