Post-Doctoral Fellow

University of Colorado Anschutz Medical Campus

Department: Medicine/Pulmonary Sciences and Critical Care

Job Title: Post-Doctoral Fellow

Position #00828016 - Requisition #35086

Job Summary:

The Consortium for Applied Microbial Metrics, CAMM (microbialmetrics.org), is a multi-institutional collaboration of investigators with a shared goal: to develop new pharmacodynamic (PD) markers that will accelerate pre-clinical drug development and human trials in mycobacterial diseases, including tuberculosis (TB) and non-tuberculosis lung disease. As a platform for cross-disciplinary collaborative innovation, the Consortium is developing practical new solutions to accelerate drug and regimen development for tuberculosis and other mycobacterial diseases while providing novel insights into disease pathogenesis. The Consortium is committed to the highest standards in research reproducibility and transparency. The Consortium is in a phase of rapid growth as key not-for-profit, federal and pharma stakeholders seek to utilize our novel drug-evaluation tools.

The Consortium for Applied Microbial Metrics has an opening for a full-time post-doctoral fellow. The primary focus of the post-doctoral fellow will be harnessing our novel pathogen-targeted SEARCH-TB RNA-seq platform for understanding of TB pathogenesis and use as a pharmacodynamic tool for evaluation of drug and regimen activity. As described in recent publications (PMID: 37905920, 39229030), SEARCH-TB represents a major advance beyond conventional crude culture-based enumeration of bacterial burden, providing highly-granular information about M. tuberculosis physiologic processes. We seek an individual with strong coding and analysis skills and a passion for microbial physiology. The post-doctoral fellow will design experiments and conduct analyses. This position does not involve hands-on laboratory or animal work. The person in this position will work with CAMM investigators on all aspects of the research process including the design of new studies, data analysis, grant writing, preparation of abstracts, talks, and manuscripts.

Key Responsibilities:

• Independently design experiments to be conducted in vitro and in murine models
• Conduct analyses of SEARCH-TB RNA-seq results and interpret biological results
• Prepare manuscripts, complete reports and assist with grant and proposal submissions related to bacterial physiology

Additional Duties and Responsibilities:

• Attends meetings and scientific conferences, as needed.

Work Location:

Hybrid - this role is eligible for a hybrid schedule and as needed for in-person meetings; onsite location is at the Anschutz Medical Campus in Aurora, Colorado and schedule will be coordinated with supervisor.

Why Join Us:

About the Division of Pulmonary Sciences and Critical Care Medicine

Thank you for your interest in the Division of Pulmonary Sciences and Critical Care Medicine at the University of Colorado! Our over 140 faculty are located across four sites: the University of Colorado Anschutz Medical Campus, National Jewish Health, Denver Health, and the VA Eastern Colorado Health Care System.

We are very proud of our long and illustrious history. Many seminal discoveries in pulmonary and critical care medicine occurred here in Denver, including advances in tuberculosis, interstitial lung disease, airway disease, cancer, and critical care. Many of our former trainees have taken leadership roles in academic medicine, including Division and Department Chairs, Deans, and American Thoracic Society Presidents.

We continue to enhance all aspects of our division and training program, and as a result, we have seen tremendous and sustained growth. The clinical practice sites have built new hospitals, and there are multiple new research buildings across the campuses. We have been fortunate to recruit tremendous new faculty members while retaining many of our former trainees.

About the University of Colorado Anschutz Medical Campu

The University of Colorado Anschutz Medical Campus is a world-class medical destination at the forefront of transformative science, medicine, education, and patient care. The campus encompasses the University of Colorado health professional schools, more than 60 centers and institutes, and two nationally ranked independent hospitals - UCHealth University of Colorado Hospital and Children's Hospital Colorado - that treat more than two million adult and pediatric patients each year. Innovative, interconnected and highly collaborative, the University of Colorado Anschutz Medical Campus delivers life-changing treatments, patient care and professional training and conducts world-renowned research fueled by over $650 million in research grants. For more information, visit www.cuanschutz.edu.

Why work for the University?

The University of Colorado offers a comprehensive benefits package. To see what benefits are available for Post-Doctoral Fellows, please visit:

Payroll & Benefits Orientation for Post-Doctoral Fellows | University of Colorado (cu.edu)

benefits guide cover-post-doc-2024 (cu.edu)

Diversity and Equity:

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community and all veterans. In addition, the Anschutz Campus has also been recognized as an Age-Friendly University. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications:

Minimum Qualifications:

Applicants must meet minimum qualifications at the time of hire.

• PhD in Microbiology, Molecular Biology, Genetics, Bioinformatics, Biostatistics, Computational Biology, or other closely related field
• Minimum of two (2) years' experience in a molecular biology laboratory or closely related experience

Knowledge, Skills, and Abilities:

• Expertise in molecular biology techniques, RNA-seq and qPCR
• Candidate with postdoctoral training, scholar awards, and one or more first-author microbiology-related publications will be highly preferred.
• A strong knowledge of R or other statistical software.
• Strong written and oral communication skills
• Ability to collaborate with global research partners in a diverse scientific setting
• Strong, independent problem-solving ability
• Ability to work independently as well as on a team
• Excellent organizational and documentation skills.

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
2. Curriculum vitae / Resume
3. Five professional references, including name, address, phone number (mobile number if appropriate), and email address

Only complete applications will be reviewed.

Reference checks are a standard step in our hiring process. You may be asked to provide contact information, including e-mail addresses, for up to 5 references if you are referred to the Hiring Authority for an interview. We will notify you prior to contacting both on and off-list references.

Applications are accepted electronically ONLY at www.cu.edu/cu-careers.

Questions should be directed to: Chantal Underkofler at Chantal.underkofler@cuanschutz.edu

Screening of Applications Begins:

Applications will be accepted until finalists are identified, but preference will be given to complete applications received by October 31, 2024. Those who do not apply by this date may or may not be considered.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as HIRING RANGE:

$61,008-74,088

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

ADA Statement:

The University will provide reasonable accommodation to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.