Principal Laboratory Sciences Professional

University of Colorado Anschutz Medical Campus

School of Medicine | Department of Medicine | Division of Rheumatology

Job Title: Principal Laboratory Sciences Professional

Position: #00815432 - Requisition: #34735

Job Summary:

The Research Service Principal Laboratory Sciences Profession position performs research on the disease mechanisms that drive rheumatoid arthritis and other autoimmune disease. The Jonsson lab specializes in human immunology, using cells from human blood and tissues to model the cellular and molecular drivers of disease. Mouse models of inflammatory arthritis are also used. This position will primarily involve performing experiments to investigate the role of T cells and other immune cells in driving inflammation. For example, an experiment might involve isolating T cells from a human blood sample, co-culturing them with some form of stimulus, and then measuring the response using a variety of techniques. The experiments will involve human cells or samples in some cases and mouse cells or tissues in others. This position will also include some amount of work with live mice. The work will be a mixture of independent work and professional, respectful, and enthusiastic interactions with researchers and sometimes patients. For candidates interested in and with some experience with computational analysis (not required), there may be opportunities to use these skills for data analysis.

Key Responsibilities:

• Collaborate with and support Principal Investigators (PI) and other stakeholders with laboratory and research functions.
• Utilize a variety of laboratory techniques required for research projects.
• Perform experiments and tabulate and analyze research.
• Process human blood and tissue samples for storage (cryopreservation) and experiments.
• Perform tissue and cell staining for flow cytometry and microscopy experiments.
• Perform tissue cell culture.
• Perform in vitro cell co-culture and stimulation experiments with read-outs such as ELISA, flow cytometry, or RT-PCR.
• Perform initial image processing of microscopy data.
• Make buffers and other reagents necessary for lab work.
• Provide animal care related to research studies, as necessary (e.g., weaning of litters from breeding pairs, monitoring of mice undergoing mouse models of inflammatory arthritis).

Work Location:

Onsite - this role is expected to work onsite and is located in Aurora, CO.

Why Join Us:

The Jonsson lab is new lab on the Anschutz campus - a very exciting time in the lifecycle of a lab. Dr. Jonsson moved to CU Anschutz in summer 2023 after spending the last eight years doing research in the lab of world-renowned immunologist and arthritis biologist, Dr. Michael Brenner. During that time, she also worked with a large nationwide research consortium that applied cutting-edge technologies to human tissue samples. Her research will leverage discoveries from these high-profile research collaborations to inform her cellular and molecular immunology studies of autoimmune disease.

In addition to her links to the larger rheumatology research community, Dr. Jonsson's lab also offers the benefits of working in a smaller lab, namely more interactions with the principal investigator and abundant opportunities for growth as a scientist and researcher. Motivated candidates will have opportunities to learn and gain expertise in many different techniques. Exposure to both mouse and human immunology as well as a range of techniques and experimental approaches is valuable for candidates considering graduate school in the future.

The work will take place in a sunny space in a large open-concept lab area that houses several labs in the Division of Rheumatology. The building is surrounded by lawns, trees, and walkways in the center of the beautiful CU Anschutz Medical Campus.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 10/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Diversity and Equity:

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnically minoritized individuals, persons with disabilities, persons within the LGBTQ+ community and all veterans. In addition, the Anschutz Campus has also been recognized as an Age-Friendly University. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications:

Minimum Qualifications:

• Bachelor's degree in biology, molecular biology, chemistry, genetics, or related field.
• Three (3) years professional level research experience.

A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis.

Applicants must meet minimum qualifications at the time of hire.

Preferred Qualifications:

• Master's degree in biology, molecular biology, chemistry, genetics, or related field.
• Four (4) years of experience in an experimental or wet laboratory.

Knowledge, Skills and Abilities:

• Expert knowledge of laboratory techniques including safety procedures and techniques.
• Expert ability to analyze and solve complex problems.
• Ability to communicate effectively, both in writing and orally.
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
• Outstanding customer service skills.
• Demonstrated commitment and leadership ability to advance diversity and inclusion.
• Knowledge of basic human anatomy, physiology, and medical terminology.
• Ability to interpret and master complex research protocol information.
• Expert level knowledge of cellular and molecular biology/immunology techniques and analysis such as cryopreservation of cells, mouse tissue and organ harvest, tissue disaggregation, cell culture and stimulation, cell isolation using magnetic columns or flow sorting, extracellular and intracellular analytic flow cytometry including data analysis, RNA isolation and RT-PCR including analysis, and/or immunofluorescence microscopy and image collection.

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email addre

Questions should be directed to: Anna Helena Jonsson, annahelena.jonsson@cuanschutz.edu

Screening of Applications Begins:

Immediately and continues until September 3rd, 2024.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as: $60,882 - $77,442.

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.